What is Progeria
Progeria is a very rare genetic disease that affects one in every 8 million people born, and has a worldwide incidence of one in every 20 million. It is caused by a point mutation in one of the two copies of the LMNA gene present in the human genome (DNA), where a thymine replaces a cytosine (specifically in the 11th exon, at locus 1824 of the gene in question). More rarely, HGPS can be caused by other mutations in the same gene.
Research history
Progeria was first described medically by Jonathan Hutchinson in 1886 and later by Hastings Gilford in 1897, doctors after whom it was named. Since progeria is caused by a random mutation in the genome, and since research has shown no specific correlation between the environment and the incidence of progeria, we can be sure that...
Ongoing experiments
From the discovery of the gene to the present day, much research has been carried out on progeria, and although not everything has yet been clarified about this interesting disease, many discoveries have also been made, some of which have resulted in clinical trials on patients.
